Abstract
Objective
To assess the most common micro-organisms causing odontogenic infections and their antimicrobial susceptibility.
Methods
The study was conducted in 80 patients with orofacial infection. The pus sample was collected, cultured (aerobically and anaerobically) and stained for morphological study of the isolates. Antibiotic sensitivity test for the isolates were performed.
Results
A total of 109 micro-organisms were isolated, no pathogenic organism were isolated in 3 cases. Out of 109 micro-organism isolated, 107 bacteria and 2 fungi were identified. Pure aerobes were identified in 28(35%) of cases, pure anaerobes in 18(22.5%), mixed aerobes and anaerobes in 10(12.5%), mixed aerobes in 15(18.75%) and mixed anaerobes were isolated in 6(7.5%) cases. Among the entire pure gram positive isolates, ofloxacin was the most sensitive drug 83.33% followed by ciprofloxacin 76.2% and sparfloxacin 76.2%. The most resistant drugs were amoxicillin (92.85%) and ampicillin (92.85%). Cefotaxime was found sensitive in 75% of pure gram negative isolates.
Conclusion
Ofloxacin was the most sensitive drug followed by ciprofloxacin and sparfloxacin for pure gram positive isolates. The most resistant drugs were amoxicillin and ampicillin. The gram negative colonies were sensitive to Cefotaxime.
Keywords: Microbiological flora, Dentoalveolar abscess, Antibiotic sensitivity
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References
- 1.Simpson A.J.H. Rational antibiotic therapy. Surgery. 2002;20(8):177–179. [Google Scholar]
- 2.Helstad A.G., Kimball J.L., Maki D.G. Recovery of anaerobic, facultative and aerobic bacteria from clinical specimens in three anaerobic transport system. J Clin Microbiol. 1977;5(6):564–569. doi: 10.1128/jcm.5.6.564-569.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Gill Y., Scully C. Orofacial odontogenic infections: Review of microbiology and current treatment. Oral Surg Oral Med Oral Pathol. 1990;70(2):155–158. doi: 10.1016/0030-4220(90)90109-6. [DOI] [PubMed] [Google Scholar]
- 4.Kannangara D.W., Thadepalli H., McQuirter J.L. Bacteriology and treatment of dental infections. Oral Surg Oral Med Oral Pathol. 1980;50(2):103–109. doi: 10.1016/0030-4220(80)90194-2. [DOI] [PubMed] [Google Scholar]
- 5.Bartlett J.G., O’Keefe P. The bacteriology of perimandibular space infections. J Oral Surg. 1979;37(6):407–409. [PubMed] [Google Scholar]
- 6.Krishnan V., Johnson J.V., Helfrick J.F. Management of Maxillofacial infections: a review of 50 cases. J Oral Maxillofac Surg. 1993;51(8):868–873. doi: 10.1016/S0278-2391(10)80105-3. [DOI] [PubMed] [Google Scholar]
- 7.Hunt D.E., King T.J., Fuller G.E. Antibiotic susceptibility of bacteria isolated from oral infections. J Oral Surg. 1978;36(7):527–529. [PubMed] [Google Scholar]
- 8.Wang J., Ahani A., Pogrel M.A. A five-year retrospective study of odontogenic maxillofacial infections in a large urban public hospital. Int J Oral Maxillofac Surg. 2005;34(6):646–649. doi: 10.1016/j.ijom.2005.03.001. [DOI] [PubMed] [Google Scholar]
- 9.Obayashi N., Ariji Y., Goto M., et al. Spread of odontogenic infection originating in the maxillary teeth: computerized tomographic assessment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;98(2):223–231. doi: 10.1016/j.tripleo.2004.05.014. [DOI] [PubMed] [Google Scholar]
- 10.Parker M.I., Khateery S.M. A retrospective analysis of orofacial infection requiring hospitalization in Al-Madinah, Saudi Arabia. Saudi Dent J. 2001;13(2):96–100. [Google Scholar]
- 11.Storoe W., Haug R.H., Lillich T.T. The changing face of odontogenic infections. J Oral Maxillofac Surg. 2001;59(7):739–748. doi: 10.1053/joms.2001.24285. [DOI] [PubMed] [Google Scholar]
- 12.Stefanopoulos P.K., Kolokotronis A.E. The clinical significance of anaerobic bacteria in acute orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;98(4):398–408. doi: 10.1016/j.tripleo.2004.01.016. [DOI] [PubMed] [Google Scholar]
- 13.Gill Y., Scully C. The microbiology and management of acute dentoalveolar abscess: views of British Oral and Maxillofacial Surgeons. Br J Oral Maxillofac Surg. 1988;26(6):452–457. doi: 10.1016/0266-4356(88)90065-4. [DOI] [PubMed] [Google Scholar]
- 14.Chow A.W., Roser S.M., Brady F.A. Orofacial odontogenic infections. Ann Intern Med. 1978;88(3):392–402. doi: 10.7326/0003-4819-88-3-392. [DOI] [PubMed] [Google Scholar]
- 15.Khosla V.H. Tuberculous osteomyelitis of the mandible: report of case. J Oral Surg. 1970;28(11):848–853. [PubMed] [Google Scholar]
- 16.McManners J., Samaranayake L.P. Suppurative oral candidiasis. Review of literature and report of a case. Int J Oral Maxillofac Surg. 1990;19(5):257–259. doi: 10.1016/S0901-5027(05)80413-8. [DOI] [PubMed] [Google Scholar]
- 17.Labriola J.D., Mascaro J., Alpert B. The microbiologic flora of Orofacial abscesses. J Oral Maxillofac Surg. 1983;41(11):711–714. doi: 10.1016/0278-2391(83)90186-6. [DOI] [PubMed] [Google Scholar]
- 18.Kuriyama T., Nakagawa K., Karasawa T., Saiki Y., Yamamoto E., Nakamura S. Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90(5):600–608. doi: 10.1067/moe.2000.109639. [DOI] [PubMed] [Google Scholar]
- 19.Peterson: Contemporary Oral and Maxillofacial Surgery. 4th ed. Chapt. 15; 344–355
- 20.Kuriyama T., Nakagawa K., Karasawa T., Saiki Y., Yamamoto E., Nakamura S. Past administration of betalactam antibiotics and emergence of beta lactamase producing bacteria in patients with orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;89(2):186–192. doi: 10.1067/moe.2000.102040. [DOI] [PubMed] [Google Scholar]
- 21.Sakaguchi M., Sato S., Ishiyama T., Katsuno S., Taguchi K. Characterization and management of deep neck infections. Int J Oral Maxillofac Surg. 1997;26(2):131–134. doi: 10.1016/S0901-5027(05)80835-5. [DOI] [PubMed] [Google Scholar]
- 22.Drucker D.B., Jolly M. Sensitivity of oral micro-organisms to antibiotics. Br Dent J. 1971;131(10):442–444. doi: 10.1038/sj.bdj.4802771. [DOI] [PubMed] [Google Scholar]