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. 2012 Sep 24;7(9):e46312. doi: 10.1371/journal.pone.0046312

Figure 2. Arteriolar and venule remodeling in dorsal skinfold window chamber is differentially altered by bone marrow specific loss of CCR2 and CX3CR1.

Figure 2

A) Representative images of window chamber regions at day 7 and 14 from experimental groups. Insets are higher magnification images of selected regions (arrows indicate arterioles, scale bar is 300 µm). Mean arteriole (B) and venule (D) diameters were quantified in all microvascular segments for each mouse in experimental groups at day 7 and 14 (*, indicates significant difference between days within a group, and ** between groups within a day, p<0.05). Average percent change in diameter from day 7 to 14 was quantified in all arteriole (C) or venule (E) segments per mouse and averaged across experimental groups (*, indicates p<0.05 significant difference between groups). [Data represents n = 7 WT→WT, n = 4 CX3CR1−/−→WT, and n = 6 CCR2−/−→WT mice per group].