Table 3. Previously reported associations between enamel formation genes and caries susceptibility.

Genes Studied	Stayton et al. [2005]	Deeley et al. [2008]	Patir et al. [2008]
Ameloblastin	−	−	+
Amelogenin	−	+	+
Enamelin	−	−	+*
Tuftelin	+*	+#	+
Tuftelin interacting protein 11	−	−	−

^*In the presence of Streptococcus mutans.

^#Only is less severely affected cases.