Table 2.
Results of maximum likelihood analysis of main / internal validation study data on 924 women (nm = 624; nv = 300) at their 4th study visit: Estimates of primary model parameters
Assuming differential misclassificationa | |||
---|---|---|---|
Variable | (std. error) | Estimated OR (95% CI) | |
Race/Ethnicity (Black vs. White/Hispanic) | 1.13 (0.22) | 3.10 (2.01 – 4.77) | |
Risk Group (IDU vs. sex) | 0.62 (0.24) | 1.86 (1.17 – 2.95) | |
HIV Status (positive vs negative) | 0.20 (0.25) | 1.22 (0.75 – 1.98) | |
Age (years) | −0.07 (0.02) | 0.94 (0.90 – 0.97) |
Assuming non-differential misclassificationb | |||
---|---|---|---|
Variable | (std. error) | Estimated OR (95% CI) | |
Race/Ethnicity (Black vs. White/Hispanic) | 1.16 (0.22) | 3.18 (2.07 – 4.86) | |
Risk Group (IDU vs. sex) | 0.98 (0.21) | 2.67 (1.76 – 4.04) | |
HIV Status (positive vs negative) | −0.10 (0.22) | 0.90 (0.59 – 1.38) | |
Age (years) | −0.08 (0.02) | 0.93 (0.89 – 0.96) | < 0.001 |
Sensitivity and specificity assumed to vary with the binary variables HIV risk group, HIV status, and Age (> median vs. < median), via model (14)
No covariates affecting sensitivity and specificity; this assumption is not supported by the data (P<0.001)