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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Immunol. 2012 Aug 29;189(7):3741–3750. doi: 10.4049/jimmunol.1201162

Figure 6. CD11b+ splenic macrophages from Irf5−/− mice display enhanced phagocytosis.

Figure 6

(A) PECs were collected from Irf5+/+ (wt) and Irf5−/− littermates 4 wks post-pristane injection. Expression of activation/maturation surface markers I-A (MHC II) and CD86 were examined on CD11b+Ly6G− monocytes. n = 5 mice per genotype. (B) Splenic macrophages from Irf5+/+ and Irf5−/− mice were isolated by positive selection and in vitro phagocytosis determined by measuring fluorescein counts. n = 4–5 per genotype; **p < 0.01 by unpaired Students t test.