Figure 6. The effects of nitric oxide on Klotho expression in mpkDCT4 cells.
Cells were treated with SNAP for 20 hours with medium changed every 5 hours. Klotho expression was measured with real-time PCR (A) and the corresponding NO production was measured in medium using Nitric Oxide Quantitation Kit (Active Motif) (B). (* p<0.05 control vs. SNAP treatment; values above bars in (B) indicate the mean NOx concentration in medium).