Table 3.
Ganciclovir (20mg/kg/day for 30 days) slows RCMV-accelerated TVS inallografts from acutely infected recipients (ARI) but not in allografts from latently infected donors (LDI).
| Group | n= | Infection Day |
POD | Histological Presentation |
Neoinimal Index (TVS)+/−SD |
|---|---|---|---|---|---|
| LDI | 8 | −180 | 54 | Chronic Rejection | 63+/−7 |
| LDI+Ganciclovir | 6 | −180 | 52 | Chronic Rejection | 65+/−3 |
| ARI | 6 | 1 | 43 | Chronic Rejection | 80+/−5 |
| ARI+Ganciclovir | 6 | 1 | 75* | Chronic Rejection | 65+/−4** |
vs. POD ARI p<0.001,
vs. ARI NI p<0.001