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. Author manuscript; available in PMC: 2012 Sep 24.

Published in final edited form as: Circ Res. 1989 Oct;65(4):997–1020. doi: 10.1161/01.res.65.4.997

Graphs showing sensitivity functions for the four-region capillary-endothelial-interstitial cell model. Upper curves show the model responses to a dispersed input function [h(t)] for both a vascular reference solute (h_R) and a permeating solute h_D. Lower panels show sensitivity function [S(t)] for several parameters. Left panel: PS_g and PS_ecl are relatively low. Right panel: With higher PS_g, the sensitivities to more distant events, governed by PS_pc and V_pc, are increased. (For definition of terms, refer to Figure 1.)

Graphs showing sensitivity functions for the four-region capillary-endothelial-interstitial cell model. Upper curves show the model responses to a dispersed input function [h(t)] for both a vascular reference solute (h_R) and a permeating solute h_D. Lower panels show sensitivity function [S(t)] for several parameters. Left panel: PS_g and PS_ecl are relatively low. Right panel: With higher PS_g, the sensitivities to more distant events, governed by PS_pc and V_pc, are increased. (For definition of terms, refer to Figure 1.)