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. 2012 Sep 14;55(9):337–343. doi: 10.3345/kjp.2012.55.9.337

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Copyright © 2012 by The Korean Pediatric Society

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Effects of leptin and the GnRH antagonist (cetrorelix) on the hypothalamic KiSS-1 gene expression. (A) Gene expression levels 2 hours after intracerebroventricular (ICV) injection. (B) Gene expression levels 4 hours after ICV injection. The KiSS-1 mRNA expression level significantly decreased in the leptin group and increased in the cetrorelix group. The KiSS-1 mRNA expression level decreased significantly in the cetrorelix+leptin group as compared with the cetrorelix and control groups. The values are the means±standard error. ^*P<0.01 versus the control group. ^**P<0.01 versus the cetrorelix group.