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. 2012 Aug 27;30(28):3493–3498. doi: 10.1200/JCO.2012.42.6635

Table 4.

Unadjusted Associations With Mortality

Characteristic Hazard Ratio 95% CI P
Signet ring cell histology 1.06 1.00 to 1.12 .070
Age at diagnosis 1.01 1.00 to 1.01 < .001
Female sex 1.04 0.99 to 1.10 .135
Race/ethnicity, %
    Black 1.04 0.96 to 1.14 .317
    API 0.74 0.69 to 0.81 < .001
    AIA 1.33 1.02 to 1.72 .032
    Hispanic ethnicity 1.09 1.02 to 1.17 .013
Surgical resection 0.25 0.24 to 0.26 < .001
AJCC stage
    1B 0.98 0.85 to 1.13 .766
    2 1.35 1.19 to 1.53 < .001
    3A 2.13 1.88 to 2.41 < .001
    3B 1.86 1.54 to 2.26 < .001
    4 5.36 4.82 to 5.95 < .001
Tumor stage
    2A 0.70 0.61 to 0.81 < .001
    2B 1.02 0.92 to 1.12 .740
    3 1.30 1.18 to 1.43 < .001
    4A 2.73 2.48 to 2.99 < .001
    4B 4.11 3.73 to 4.54 < .001
Node stage
    1 1.33 1.24 to 1.41 < .001
    2 1.19 1.08 to 1.30 < .001
    3 1.63 1.45 to 1.84 < .001
Metastases stage 1 4.10 3.88 to 4.33 < .001
Tumor grade
    2 1.55 1.28 to 1.89 < .001
    3 2.06 1.71 to 2.49 < .001
    4 2.04 1.59 to 2.60 < .001
Radiation therapy administered 0.43 0.37 to 0.49 < .001
Radiation before surgery 0.38 0.35 to 0.41 < .001
Radiation after surgery 0.45 0.19 to 0.66 < .001

Abbreviations: AIA, American Indian/Alaska Native; AJCC, American Joint Committee on Cancer, 6th edition; API, Asian/Pacific Islander.