Skip to main content
. 2007 Nov 28;24(11):491–505. doi: 10.1007/s10815-007-9142-9

Table 1.

Selected cytokines in implantation versus post-implantation events

Cytokine Implantation Post-implantation (abortion/resorption)
Success Failure Success Failure
IL-1 Ab neut (?) Helps
IL-2 High doses cause High doses cause
IL-3 High doses help High doses prevent
IL-4 High doses help
IL-5 No effect No effect
IL-6 High doses cause (?) High doses (?)
IL-8 ND ND
IL-10 No effect Helps in resorb prone strains
IL-11 KO causes
IL-12 High doses cause High doses cause
IL-13 Causes (?)
IL-15 KO no effect except arteries KO no effect except arteries
IL-18 High doses cause High doses cause
IL-23 High doses cause ND
IL-27 High doses cause High doses cause
LIF KO causes
CSF-1 KO causes
GM-CSF KO no effect Prevents KO increases
TNF-α High doses cause High doses cause
IFN-γ KO no effect High doses cause
TGF-α Required for adhesion ND
TGF-βs Prevents KO may cause (?)