Table I.
Effect of HB-EGF on Attachment and Outgrowth of Mouse Embryos Treated at 2-cell Stage (post hCG 48 h)
| No. (%) of developed embryos | |||||
|---|---|---|---|---|---|
| Treatment | No. of total embryos | Attached embryos | Outgrowth embryos | No. (%) of unattached embryos | |
| Attached/outgrowth (144 h) | Controla | 70 | 27 (36.8±1.8)d | 20 (28.9±1.9) | 23 (37.2±0.3) |
| HB-EGFb | 73 | 21 (28.6±0.9) | 31 (42.5±1.7)* | 21 (28.9±1.6) | |
| HB-EGF& and Abc | 67 | 22 (32.8±0.7) | 19 (28.4±0.9) | 26 (43.5±0.9) | |
aThe control was KSOM only.
bHB-EGF, heparin-binding epidermal growth factor.
cAb, anti-HB-EGF antiserum.
dValues are obtained from three different experiments. Data are expressed as the mean ± SEM.
*Significantly different from control, p < 0.01.