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. Author manuscript; available in PMC: 2013 Oct 25.
Published in final edited form as: Neuroscience. 2012 Aug 11;223:200–208. doi: 10.1016/j.neuroscience.2012.08.008

Table 1.

Multivariate two-way ANOVA main effects, interactions, and P values for EPMZ behavioral parameters in sham-lesioned, crossed IBO-lesioned, and ipsilateral IBO-lesioned rats after i.p. saline or YO.

Effect Source EPMZ parameter F P <
I.p. treatment [F(1,62)]
Saline vehicle vs. YO (1.0 mg/kg)
Open arm time ratio 18.6 * 0.001
Open arm entries 16.7 * 0.001
Closed arm entries 25.5 * 0.001
Total entries 35.2 * 0.001

Surgical group [F(2,62)]
Sham vs. crossed IBO vs. ipsi IBO lesioned
Open arm time ratio 3.3 * 0.04
Open arm entries 2.2 n.s. (P=0.12)
Closed arm entries 2.7 n.s. (P=0.08)
Total entries 3.7 * 0.03

Interaction [F(2,62)]
Surgical group x i.p. treatment
Open arm time ratio 6.4 * 0.003
Open arm entries 2.6 n.s. (P=0.08)
Closed arm entries 2.8 n.s. (P=0.07)
Total entries 2.3 n.s. (P=0.11)

See Figure 3 for graphical display of data and post-hoc comparisons. ns, not significant.