Table 3.
Up and down regulated genes in selected DHA-resistant clone DHA1 during IDC.
| Gene ID | Gene description | Fold change (DHA1/Dd2)
|
||
|---|---|---|---|---|
| Ring | Trophozoite | Schizont | ||
| PF10_0336 | Conserved Plasmodium protein, unknown function | 9.2 | 6.4 | 5.0 |
| PF14_0164 | NADP-specific glutamate dehydrogenase | 3.1 | 3.0 | 2.4 |
| PF14_0463 | Chloroquine resistance marker protein | 3.0 | 2.8 | 3.4 |
| PFE1150w | Multidrug resistance protein 1 (pfmdr1) | 6.2 | 8.6 | 9.8 |
| PFF1130c | Superoxide dismutase | 4.8 | 2.5 | 2.6 |
| PFI0925w | Gamma-glutamylcysteine synthetase | 2.5 | 2.8 | 3.1 |
| PFI1250w | Thioredoxin-like protein 2 | 2.8 | 3.4 | 4.7 |
| PFL0725w | Thioredoxin peroxidase 2 | 2.5 | 2.0 | 2.2 |
| PF08_0054 | Heat shock protein 70 | 2.1 | 2.1 | 2.1 |
| PFI1780w | Plasmodium exported protein (PHISTc), | 66.0 | 21.4 | 5.1 |
| MAL7P1.58 | Pfmc-2TM | 8.9 | 62.0 | 13.0 |
| PFB0100c | Knob-associated histidine-rich protein | 8.7 | 3.1 | 2.2 |
| PFI1805w | Rifin | 15.7 | 3.0 | 2.0 |
| PFF0280w | Conserved Plasmodium protein, unknown function | 2.2 | 2.5 | 2.3 |
| PF13_0235 | Transcription factor with AP2 domain(s), putative | 3.5 | 4.2 | 2.8 |
| PFD0150w | Conserved Plasmodium protein, unknown function | 4.1 | 2.0 | 2.4 |
| PFD0295c | Apical sushi protein | −8.2 | −2.0 | −4.4 |
| PF10_0331a | Conserved Plasmodium protein, unknown function | −2.0 | −2.4 | −2.5 |
| PFC0345w | Conserved Plasmodium protein, unknown function | −7.7 | −4.1 | −9.4 |