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Minimal improvement in mid-diaphyseal cortical bone volume with DHT treatment during LT intervention as assessed by μCT analysis. A. Changes in WT mice in femoral bone volume, cortical thickness and marrow volume (n = 10–11). B. Assessment of mid-diaphyseal bone in AR2.3-tg mice (n = 7–11). C. Analysis of mid-diaphyseal bone by μCT in AR3.6-tg mice (n = 8–11). All data expressed as mean ± SEM. * p < 0.05, ** p < 0.01 vs. sham control; # p < 0.05; + p < 0.05, ++ p < 0.01 vs. WT sham.
