Abstract
Coccidioidomycosis is a disease caused by Coccidioides immitis, a soilinhabiting fungus endemic to the desert climate of the southwestern United States and Central and South America. We report a case of disseminated coccidioidomycosis in a previously healthy person living in New York City, who was initially thought to have tuberculosis. The incidence of coccidioidomycosis has been increasing in both endemic and nonendemic areas, but diagnosis is often delayed or missed in nonendemic areas, resulting in extensive and unnecessary medical workup for other diseases or progression to serious disease. Therefore, clinicians should increase their awareness and consideration of this disease in patients with chronic systemic illness.
Keywords: Coccidioidomycosis, Diagnosis, Disseminated
Full Text
The Full Text of this article is available as a PDF (251.5 KB).
References
- 1.Posadas A. Un nuovo caso de micosis fungoides con psorospermias. Anales Dell Circulo Médico Argentino, Buenos Aires. 1892;15:585–597. [Google Scholar]
- 2.Wernicke RJ. Pentastomas. Revista de la Sociedad Medica Argentina. 1892;1:186–189. [Google Scholar]
- 3.Rixford E. Case for diagnosis presented before the San Francisco Medico-Chirurgical Society, March 5, 1894. Occidental Medical Times. 1894;8:326–326. [Google Scholar]
- 4.Rosenstein NE, Emery KW, Werner SB, et al. Risk factors for severe pulmonary and disseminated coccidioidomycosis: Kern County, California, 1995–1996. Clin Infect Dis. 2001;32:708–715. doi: 10.1086/319203. [DOI] [PubMed] [Google Scholar]
- 5.Rutala PJ, Smith JW. Coccidioidomycosis in potentially compromised, hosts: the effect of immunosuppressive therapy in dissemination. Am J Med Sci. 1978;275:283–295. doi: 10.1097/00000441-197805000-00006. [DOI] [PubMed] [Google Scholar]
- 6.Jones JL, Fleming PL, Ciesielski CA, Hu DJ, Kaplan JE, Ward JW. Coccidioidomycosis among persons with AIDS in the United States. J Infect Dis. 1995;171:961–966. doi: 10.1093/infdis/171.4.961. [DOI] [PubMed] [Google Scholar]
- 7.Peterson CM, Schuppert K, Kelly PC, Pappagianis D. Coccidioidomycosis and pregnancy. Obstet Gynecol Surv. 1993;48:149–156. doi: 10.1097/00006254-199303000-00002. [DOI] [PubMed] [Google Scholar]
- 8.Vartivarian SE, Coudron PE, Markowitz SM. Disseminated coccidioidomycosis. Unusual manifestations in a cardiac transplantation patient. Am J Med. 1987;83:949–952. doi: 10.1016/0002-9343(87)90657-7. [DOI] [PubMed] [Google Scholar]
- 9.Schneider E, Hajjeh RA, Spiegel RA, et al. A coccidioidomycosis outbreak following the Northridge, California earthquake. JAMA. 1997;277:904–908. doi: 10.1001/jama.1997.03540350054033. [DOI] [PubMed] [Google Scholar]
- 10.Kirkland TN, Fierer J. Coccidioidomycosis: a reemerging infectious disease. Emerg Infect Dis. 1996;2:192–199. doi: 10.3201/eid0203.960305. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Cardone JS, Vinson R, Anderson LL. Coccidioidomycosis: the other great imitator. Cutis. 1995;56:33–36. [PubMed] [Google Scholar]
- 12.Rance BR, Elston DM. Disseminated coccidioidomycosis discovered during routine skin cancer screening. Cutis. 2002;70:70–72. [PubMed] [Google Scholar]
- 13.Quimby SR, Connolly SM, Winkelmann RK, Smilack JD. Clinicopathologic spectrum of specific cutaneous lesions of disseminated coccidioidomycosis. J Am Acad Dermatol. 1992;26:79–85. doi: 10.1016/0190-9622(92)70011-4. [DOI] [PubMed] [Google Scholar]
- 14.Galgiani JN. Coccidioidomycosis: a regional disease of national importance. Ann Intern Med. 1999;130:293–300. doi: 10.7326/0003-4819-130-4-199902160-00015. [DOI] [PubMed] [Google Scholar]
- 15.Graybill JR, Stevens DA, Galgiani JN, et al. Itraconazole treatment of coccidioidomycosis. Am J Med. 1990;89:282–290. doi: 10.1016/0002-9343(90)90339-F. [DOI] [PubMed] [Google Scholar]
- 16.Catanzaro A, Galgiani JN, Levine BE, et al. Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis. NIAID Mycoses Study Group. Am J Med. 1995;98:249–256. doi: 10.1016/S0002-9343(99)80371-4. [DOI] [PubMed] [Google Scholar]
- 17.Increase in coccidioidomycosis-Arizona 1998–2001. Morbidity and Mortality Weekly Report. Centers for Disease Control and Prevention. 2003; 52;109–112. Available at: http://www.cdc.gov/mmwr. Accessed October 10, 2003. [PubMed]
- 18.Chaturvedi V, Ramani R, Gromadzki S, et al. Coccidioidomycosis in New York State. Emerg Infect Dis. 2000;6:25–29. doi: 10.3201/eid0601.000104. [DOI] [PMC free article] [PubMed] [Google Scholar]