Table 3.

Autoantibody titers for organ donors. Autoantibody levels were determined by RIA as described in Methods.

Donor Type	CaseID	Age (yr)	Gender	Race	AutoAb Summary (RIA) A	GADA	IA2A	ZnT8A	mIAA
No diabetes	6117	0.33	M	Caucasian	Negative	1	0	−0.012	0.000
No diabetes	6115	0.40	M	Caucasian	Negative	11	0	−0.009	0.002
No diabetes	6125	0.42	M	Caucasian	Negative	0	1	0.001	−0.001
No diabetes	6122	0.42	F	Multiracial	Negative	1	0	−0.011	0.001
No diabetes	6092	0.50	F	African Am	Negative	0	0	−0.001	0.001
No diabetes	6072	1.00	F	Caucasian	No serum available
No diabetes	6107	2.00	M	African Am	Negative	0	0	−0.003	0.004
No diabetes	6103	2.00	M	Caucasian	Negative	0	0	−0.004	0.003
No diabetes	6014	2.00	M	Caucasian	No serum available
No diabetes	6106	3.00	M	Caucasian	Negative	0	0	−0.003	0.004
No diabetes	6094	3.00	M	African Am	Negative	0	0	−0.005	0.002
No diabetes	6130	5.00	M	Caucasian	Negative	0	0	−0.007	0.001
No diabetes	6005	5.00	F	Caucasian	Negative	11	0	0.017	−0.003
No diabetes	6112	6.00	F	Hispanic/Latino	Negative	0	0	−0.001	0.002
No diabetes	6047	8.00	M	Caucasian	Negative	0	0	−0.002	−0.001
No diabetes	6144	8.00	F	Hispanic/Latino	Negative	0	4	0.002	0.003
No diabetes	6137	9.00	F	Hispanic/Latino	Negative	1	0	0.001	0.000
No diabetes	6007	9.00	M		No serum available
No diabetes	6099	14.00	M	Caucasian	Negative	0	0	−0.004	0.002
No diabetes	6153	15.00	M	Hispanic/Latino	Negative	0	0	−0.002	0.005
No diabetes	6096	16.00	F	African Am	Negative	0	0	−0.003	0.003
No diabetes	6075	16.00	M	African Am	Negative	11	0	0.001	0.003
No diabetes	6098	18.00	M	Caucasian	Negative	0	0	−0.004	0.000
No diabetes	6073	19.00	M	Caucasian	Negative	0	0	−0.001	0.001
No diabetes	6024	21.00	M	Caucasian	Negative	0	0	−0.017	−0.001
No diabetes	6057	22.00	M	Caucasian	Negative	0	1	−0.002	0.001
No diabetes	6001	22.00	M	Caucasian	Negative	9	0	−0.006	−0.001
No diabetes	6003	23.00	F	Caucasian	No serum available
No diabetes	6029	24.00	F	Hispanic/Latino	No serum available
No diabetes	6131	24.00	M	Caucasian	Negative	0	2	0.001	−0.002
No diabetes	6060	24.00	M	Caucasian	Negative	0	0	−0.005	−0.001
No diabetes	6126	25.00	M	Hispanic/Latino	Negative	0	1	−0.010	0.000
No diabetes	6053	25.00	M	Caucasian	Negative	0	0	−0.002	−0.002
No diabetes	6055	27.00	M	Caucasian	Negative	0	0	−0.001	0.008
No diabetes	6058	27.00	M	Hispanic/Latino	Negative	0	0	−0.004	0.000
No diabetes	6091	27.00	M	Caucasian	Negative	0	3	0.006	0.001
No diabetes	6134	27.00	M	Caucasian	Negative	0	0	−0.005	0.001
No diabetes	6048	30.00	M	Caucasian	Negative	0	0	−0.004	0.001
No diabetes	6030	30.00	M	Caucasian	Negative	0	0	0.001	0.001
No diabetes	6034	32.00	F	Caucasian	Negative	0	0	−0.016	−0.002
No diabetes	6004	33.00	M		No serum available
No diabetes	6140	38.00	M	Caucasian	Negative	0	0	0.002	0.000
No diabetes	6015	39.00	F	Caucasian	Negative	0	0	−0.016	0.000
No diabetes	6095	40.00	M	Hispanic/Latino	No serum available
No diabetes	6104	41.00	M	Caucasian	Negative	0	0	0.001	−0.001
No diabetes	6019	42.00	M	Caucasian	Negative	0	0	−0.020	0.000
No diabetes	6129	43.00	F	Caucasian	Negative	2	1	−0.004	0.001
No diabetes	6097	43.00	F	Caucasian	Negative	0	0	0.006	0.003
No diabetes	6009	45.00	M	Caucasian	Negative	0	0	0.012	−0.003
No diabetes	6102	45.00	F	Caucasian	Negative	0	0	−0.005	0.003
No diabetes	6011	46.00	F	African Am	No serum available
No diabetes	6010	47.00	F	Caucasian	No serum available
No diabetes	6008	50.00	F	Caucasian	No serum available
No diabetes	6017	59.00	F	Caucasian	Negative	1	0	−0.015	0.001
No diabetes	6020	60.00	M	Caucasian	Negative	0	0	0.014	0.001
No diabetes	6016	64.00	F	Caucasian	No serum available
No diabetes	6013	65.00	M	Caucasian	Negative	0	0	−0.013	0.000
No diabetes	6012	68.00	F	Caucasian	Negative	0	0	−0.019	0.000
No diabetes	6021	72.00	F	Hispanic/Latino	Negative	0	0	−0.026	−0.001
No diabetes	6022	75.00	M	Caucasian	Negative	0	0	−0.018	0.001
Autoab Pos	6116	0.17	F	Hispanic/Latino	mIAA+	1	1	0.000	0.024
Autoab Pos	6090	2.00	M	Hispanic/Latino	GADA+	490	0	−0.001	−0.001
Autoab Pos	6027	19.00	M	Caucasian	ZnT8+	0	0	0.030	0.000
Autoab Pos	6123	23.00	F	Caucasian	GADA+	32	0	−0.003	0.000
Autoab Pos	6147	24.00	F	Caucasian	GADA+	290	1	0.004	0.001
Autoab Pos	6151	30.00	M	Caucasian	GADA+	53	0	−0.009	0.004
Autoab Pos	6002	39.00	M	Caucasian	mIAA+	4	0	−0.002	0.051
Autoab Pos	6156	40.00	M	Caucasian	GADA+	208	0	−0.002	0.007
Autoab Pos	6044	41.00	M	Hispanic/Latino	GADA+	748	0	−0.003	0.001
Autoab Pos	6154	48.00	F	Caucasian	GADA+	845	0	−0.005	0.006
Autoab Pos	6101	65.00	M	Caucasian	GADA+	161	0	−0.005	−0.001
Autoab Pos	6023	66.00	M	Caucasian	mIAA+	2	4	0.001	0.362
Autoab Pos	6080	69.00	F	Caucasian	GADA+ mIAA+	90	0	0.002	0.028
T1D	6063	4.00	M	Caucasian	mIAA+	0	0	0.010	0.065
T1D	6062	11.00	M	African Am	No serum available
T1D	6079	11.00	F	Caucasian	Negative	0	0	0.012	0.005
T1D	6052	12.00	M	African Am	IA-2A+ mIAA+	0	140	0.010	0.063
T1D	6113	13.00	F	Caucasian	mIAA+	0	0	0.001	0.873
T1D	6089	14.00	M	Caucasian	mIAA+	0	0	0.002	0.416
T1D	6084	14.00	M	Caucasian	mIAA+	1	0	0.000	2.155
T1D	6049	15.00	F	African Am	GADA+ mIAA+	384	2	0.017	0.392
T1D	6083	15.00	F	Caucasian	mIAA+	0	0	−0.007	0.143
T1D	6148	17.00	M	Caucasian	GADA+ mIAA+	568	1	0.013	0.043
T1D	6145	18.00	M	Caucasian	GADA+ ZnT8(+) mIAA+	664	3	0.021	0.822
T1D	6087	18.00	M	Caucasian	ZnT8+ mIAA+	0	0	0.071	0.016
T1D	6046	19.00	F	Caucasian	IA-2A+ ZnT8+	0	69	0.045	−0.003
T1D	6064	20.00	F	Caucasian	GADA+ IA-2A+ ZnT8+	38	111	0.017	0.015
T1D	6051	20.00	M	Caucasian	mIAA+	0	0	−0.001	0.052
T1D	6026	22.00	M	Caucasian	Negative	0	0	−0.009	0.031
T1D	6069	23.00	M	African Am	No serum available
T1D	6070	23.00	F	Caucasian	IA-2A+ mIAA+	11	245	0.002	0.097
T1D	6025	24.00	M	Caucasian	mIAA+	0	0	−0.012	0.019
T1D	6076	26.00	M	Caucasian	GADA+	355	0	0.008	0.018
T1D	6045	26.00	M	Caucasian	mIAA+	0	0	0.033	0.032
T1D	6041	26.00	M	Caucasian	Negative	0	0	−0.001	0.001
T1D	6119	28.00	M	Caucasian	GADA+ mIAA+	105	0	0.011	0.014
T1D	6071	28.00	F	Caucasian	IA-2A+ mIAA+	0	12	0.004	4.190
T1D	6061	28.00	M	Caucasian	mIAA+	0	0	0.029	0.022
T1D	6039	29.00	F	Caucasian	GADA+ IA-2A+ ZnT8+ mIAA+	141	135	0.112	0.017
T1D	6152	30.00	F	Caucasian	ZnT8(+)	0	3	0.021	0.001
T1D	6088	31.00	M	Caucasian	GADA+ IA-2A+ ZnT8+ mIAA+	28	37	0.070	0.364
T1D	6081	31.00	M	Hispanic/Latino	Negative	0	0	−0.003	−0.007
T1D	6035	32.00	M	Caucasian	mIAA+	0	0	−0.009	0.319
T1D	6077	33.00	F	Caucasian	mIAA+	0	0	−0.001	0.083
T1D	6067	33.00	F	Hispanic/Latino	Negative	0	0	0.002	−0.003
T1D	6143	33.00	F	Caucasian	IA-2A+ mIAA+	0	13	0.008	0.043
T1D	6121	34.00	F	Caucasian	Negative	9	0	0.017	−0.001
T1D	6128	34.00	F	Caucasian	mIAA+	1	0	−0.016	1.358
T1D	6032	34.00	M	Caucasian	mIAA+	0	0	−0.012	0.287
T1D	6054	35.00	F	Caucasian	mIAA+	0	0	0.002	0.404
T1D	6038	37.00	F	Caucasian	Negative	0	0	−0.009	−0.001
T1D	6141	37.00	M	Caucasian	GADA+ IA-2A+ ZnT8+ mIAA+	22	15	0.041	0.360
T1D	6031	39.00	M	Caucasian	mIAA+	0	0	−0.012	0.143
T1D	6033	41.00	M	Caucasian	Negative	0	0	−0.009	0.004
T1D	6150	41.00	M	Caucasian	mIAA+	0	0	−0.002	0.567
T1D	6135	44.00	M	Caucasian	GADA+ mIAA+	149	2	0.004	0.023
T1D	6036	49.00	F	African Am	mIAA+	0	0	0.008	0.055
T1D	6138	49.00	F	Caucasian	mIAA+	0	2	0.000	0.168
T1D	6040	50.00	F	Caucasian	mIAA+	0	0	0.013	0.200
T1D	6155	50.00	F	Caucasian	mIAA+	3	1	−0.003	0.061

^AAll values converted to NIDDK units and defined as positive for GADA if ≥20, IA2A if ≥5, ZnT8A if ≥0.020, and mIAA if ≥0.010.