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. 2012 Sep 21;3:375. doi: 10.3389/fphys.2012.00375

Figure 4.

Figure 4

Loss of Msx1 leads to abnormal angiogenesis. Immunostaining for the endothelial marker PECAM in coronal sections of E12.5 (A,C,E,G) Msx1+/− and (B,D,F,H) Msx1−/− embryos in increasing magnifications: 2.5× (A,B), 5× (C,D), detailed frontonasal prominence at 10× (E,F), and detailed maxillary prominence at 10× (G,H). Immunostaining for the pericyte marker Type IV collagen in coronal sections of E15.5 (I,K,M,O) Msx1+/− and (J,L,N,P) Msx1−/− embryos in increasing magnifications: 5× (I,J), 10× (K,L), detailed nasal septum at 20× (M,N), and detailed nasal cartilage at 20× (O,P). e, eye; fn, frontonasal prominence; mes, mesenchyme; mx, maxillary prominence; nc, nasal cartilage; ne, nasal ectoderm; s, nasal septum.