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. 2012 Sep 24;3:377. doi: 10.3389/fphys.2012.00377

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Copyright © 2012 d'Amaro, Scheidegger, Blumer, Pazera, Katsaros, Graf and Chiquet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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In situ hybridizations on frontal sections through E13.5 wildtype mouse embryo heads at the level of the posterior palate with RNA probes specific for (A) fibrillin-1, (B) Tgf-β 1, (C) fibrillin-2, and (D) Tgf-β3. The maxillary processes in (A,B) show increased expression of fibrillin-1 and Tgf-β1 mRNA, respectively. Note enhanced expression of fibrillin-2 in the proximal-medial mesenchyme of the palatal shelves (C), dorsal of the epithelium positive for Tgf-β3 mRNA (D). Maxillary process (mx), palatal shelf (p), tongue (t). Bars, 250 μm.