Table 3.

Contributions of the preceding and intraresidue type to the total ²H isotope shift observed for ¹⁵N in perdeuterated proteins, as described by the coefficients of Eq 3.^a

Residue type	Ci−1, ppb	Di, ppb
Ala	77 ± 10	−330 ± 10
Asp	88 ± 12	−290 ± 11
Glu	79 ± 10	−273 ± 10
Phe	59 ± 15	−252 ± 14
Gly	164 ± 10	−274 ± 10
His	77 ± 17	−311 ± 17
Ile	−21 ± 14	−200 ± 14
Lys	63 ± 11	−253 ± 8
Leu	45 ± 12	−258 ± 13
Met	73 ± 16	−259 ± 13
Asn	96 ± 13	−295 ± 13
Pro	36 ± 12	―
Gln	73 ± 11	−263 ± 15
Ser	71 ± 12	−286 ± 12
Thr	39 ± 10	−197 ± 11
Val	−35 ± 10	−235 ± 10
Tyr	87 ± 13	−253 ± 12

^aUncertainties are based on Monte-Carlo simulations assuming 14 ppb variability of measured isotope shifts (see Text).