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Summary of in vitro polymerase activity of selected Pol mutant proteins
| Polymerase mutant construct | Basal DNA polymerase activitya | Stimulated polymerase activity via UL42b |
|---|---|---|
| PolΔN43 | + | + |
| PolΔN52 | + | + |
| PolΔN67 | − | − |
| PolΔN141 | − | − |
| PolA6 | + | + |
| PolΔC1216 | + | − |
+, wild-type levels of activity; −, activity at or below that of background.
+ , wild-type levels of activity; − , activity at or below that of UL42-binding mutant protein PolΔC1216.
