Table 2.
Cross-species transmission events presumably occurring in the evolution of Murinae-associated hantaviruses
| Hosts |
Viruses |
Level | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Species |
Genetic distance | Sister virusesa |
% Nucleotide/% amino acid difference between prospecies and neospecies |
|||||||
| Donor | Receptor | Prospecies | Neospecies | S | M | Gn | Gc | L | ||
| Hylomyscus simus | Apodemus agrarius | 0.192 | SANGV | SAAV | 22.1/11.4 | 27.1/19.5 | 28.9/22.9 | 24.6/15 | 27.9/14.3 | Genus |
| A. agrarius | A. flavicllis | 0.182 | SAAV | DOBV | 13.4/2.3 | 17.3/6.0 | 17.8/6.3 | 16.7/4.3 | 13.4/2.6 | Species |
| Bandicota indica | Rattus rattus | 0.144 | THAIV | SERV | 16.4/3.0 | 20.4/7.3 | 20.5/8.3 | 20.6/6.2 | 20.8/7.6 | Genus |
| B. indica | R. norvegicus | 0.155 | THAIV | SEOV | 22.6/13.5 | 25.9/18.5 | 27.0/21.8 | 24.6/14.4 | 25.8/15.2 | Genus |
| R. norvegicus | R. rattus | 0.126 | SEOV | GOUV | 12.0/1.4 | 15.4/3.4 | 15.6/3.7 | 15.4/3.1 | - | Species |
| B. indica | N. confucianus | 0.186 | THAIV | DBSV | 24.9/15.6 | 17.4/25.0 | 29.0/26.2 | 26.7/18.7 | 29.3/19.6 | Genus |
| N. confucianus | A. agrarius | 0.202 | DBSV | HTNV | 21.8/7.9 | 23.8/15.3 | 28.2/18.1 | 22.8/11.9 | 23.9/7.5 | Genus |
| A. agrarius | A. peninsulae | 0.169 | HTNV | ASV | 17.1/3.5 | 19.4/8.8 | 20.4/11 | 18.3/6.0 | 20.8/6.0 | Species |
a
Prospecies, presumable parental/sister species of new species; neospecies, presumable descendant species.