Table 4.
Detection of positively selected sites by maximum-likelihood estimation for 48 S segment and 40 M segment sequences of hantaviruses
| Model | Positively selected site(s) (position)a | |
|---|---|---|
| S segment | M segment | |
| Branch model (M0 vs FR) | Not allowed | Not allowed |
| Site model (M7 vs M8) | None | None |
| Branch-site model A (A′ vs A) with foreground group: | ||
| ASV | None | 144, 336 |
| DBSV | None | 285, 353, 364 |
| HTNV | None | 16, 51, 84 |
| SEOV | None | None |
| GOUV | None | 916 |
| DOBV | None | 932 |
| SAAV | None | 228, 932, 1076 |
| DOBV-SAAV | 256, 408 | 10, 56*, 207*, 309, 312, 336, 351*, 355, 364*, 430*, 653, 657, 1055*, 1071 |
| DOBV-SAAV-SANGV | 256, 408 | 14, 56, 101, 122, 218, 225, 232, 261, 309, 312, 322, 331, 332, 336, 351*, 364*, 583, 653, 657, 667*, 698, 703, 714, 908 , 932, 1055, 1089, 1114 |
| HTNV-ASV | None | 5, 101, 442, 885, 1025, 1060 |
| HTNV-ASV-DBSV | None | 55, 72*, 77, 223, 230, 232, 312, 333, 556, 699, 712, 892 |
| SEOV-GOUV | 234, 255, 259 | 52*, 214, 225, 228, 232 , 261, 326, 351, 502, 567, 569*, 667, 691, 703, 979, 1025, 1093 |
| THAIV-SERV | 74, 237, 253, 258, 263, 267, 272, 283, 286, 299, 412 | 43, 101, 261, 278, 351, 521, 703, 842, 911*, 1068 , 1071*, 1074 |
| THAIV-SERV-SEOV-GOUV | None | 90*, 100**, 108, 137, 191, 195, 198, 215**, 293**, 556, 650, 701, 703, 719*, 765, 793, 883**, 892, 956 |
a
* and **, positively selected sites identified with posterior probability P > 95% or P > 99%, respectively. The positive selection sites that are also the “signature amino acid” markers are shown in boldface.