Fig 2.

HLA frequency-dependent effects on viral load and CD4 counts. The correlations between VL or CD4 count with combined frequencies for all subjects (n = 504) are shown. HLA frequencies used to calculate the combined frequencies for each individual were derived from the overall allele frequencies in the entire cohort of 504 subjects. Linear regression lines are included in the plots. The distribution of HLA class I frequencies among 504 chronically HIV-1-infected Japanese individuals used in this analysis is shown in Table S4 in the supplemental material.