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. 2012 Oct;86(19):10505–10516. doi: 10.1128/JVI.00102-12

Table 1.

Clinical characteristics of 14 HLA-B*57 participants from the MACS cohort

Participant HLA genotype Characteristics at time of sampling
Long-term outcome
Time (mo) since infectiona CD4b VLc Event Time (yr) to eventd
A A0100 A3000 B1801 B5701 C0501 C0602 0–12 833 20,501 Death 3.5
B A0201 A3301 B3501 B5701 C0401 C0602 5–6 789 14,811 Death 5.5
C A0101 A0201 B4402 B5701 C0501 C0602 0–24 317 30,468 CD4 < 200 6
D A0101 A2402 B4401 B5701 C0304 C0602 0–6 1098 8,868 CD4 < 200 6
E A0201 A0201 B5001 B5701 C0602 C0602 10–15 800 2,927 CD4 < 200 6.25
F A0101 A0201 B0702 B5701 C0602 C0702 0–6 744 11,955 CD4 < 200 9
G A0101 A0201 B5701 B5701 C0602 C0702 0–7 665 4,414 CD4 < 200 11
H A0101 A2501 B1801 B5701 C0602 C1203 0–6 1637 3,151 CD4 < 200 12
I A0201 A0201 B1501 B5701 C0304 C0602 3–8 958 4,989 cART 13
J A0100 A2400 B4403 B5701 C0303 C0602 4–6 801 43,400 Nonee 13
K A0101 A0201 B5101 B5701 C0602 C0702 0–6 757 109,373 CD4 < 200 13.5
L A0200 A3201 B0702 B5701 C0602 C0700 9–15 853 82,009 CD4 < 200 15
M A0201 A6801 B5703 B5802 C0602 C1801 6–12 642 5,538 cART 17
N A0101 A0301 B1518 B5701 C0602 C0704 0–9 1200 < 400 Nonee 25
a

Number of months that elapsed between seroconversion and donation of the samples used in this study.

b

Number of CD4+ T lymphocytes/mm3 of blood at the time of sampling.

c

Number of HIV-1 RNA copies/ml of plasma at the time of sampling.

d

Number of years elapsed between date of infection and the earliest of the following events: decline of CD4+ T cell counts below 200/mm3, initiation of combination antiretroviral therapy (cART), or death.

e

Participants J and N still had CD4 counts above 200, as of 2011.