Table 4.
Expression patterns of chemokine receptors in JC_CD8 and CL_CD8 cells from biopsy samples taken 8 weeks after healing
| Gene | Avg intensity |
No. of patients with difference ofa: |
|||
|---|---|---|---|---|---|
| CL_CD8 | JC_CD8 | >3-fold | >5-fold | >10-fold | |
| CCR1 | 173 | 381 | 5, 3 | 5, 3 | 4, 3 |
| CCR2 | 13 | 15 | 0 | 0 | 0 |
| CCR3 | 19 | 10 | 0 | 0 | 0 |
| CCR4 | 52 | 10 | 2 | 1 | 1 |
| CCR5 | 46 | 41 | 4, 1 | 2, 1 | 1 |
| CCR7 | 34 | 43 | 1, 2 | 1, 2 | 1 |
| CCR8 | 36 | 14 | 2, 2 | 1, 2 | 2 |
| CCR9 | 33 | 24 | 0 | 0 | 0 |
| CCR10 | 17 | 16 | 0 | 0 | 0 |
| CXCR3 | 12 | 26 | 2 | 1 | 1 |
| CXCR4 | 32 | 24 | 2, 2 | 2, 1 | 1 |
| CXCR5 | 36 | 35 | 1 | 1 | 0 |
| CXCR6 | 11 | 58 | 4 | 3 | 1 |
| CXCR7 | 121 | 51 | 2, 3 | 3 | 1 |
a
Number of patients in which junction CD8+ T cells (JC_CD8) from 8-week-posthealing biopsy samples had either upregulated (bold) or downregulated (italic) gene expression relative to CD8+ T cells from matched contralateral biopsy samples (CL_CD8).