Table 2.
Percentage of inhibition of cH5/1-pseudotyped particle entry using a purified IgG preparation from pooled sera
IgG concn (μg/ml) | % inhibition with: |
||||
---|---|---|---|---|---|
NC99-Cal09a | NC99-SI06b | Cal09c | 6F12d | Naïvee | |
50 | 92.0 ± 4.2 | 97.3 ± 0.9 | 9.0 ± 12.8 | 99.8 ± 0.0 | 0 ± 0 |
10 | 50.5 ± 8.8 | 64.3 ± 3.1 | 14.3 ± 4.5 | 97.5 ± 0.6 | 10.1 ± 14.3 |
2 | 0.5 ± 0.7 | 33.8 ± 19.9 | 8.0 ± 9.3 | 84.8 ± 5.4 | 4.1 ± 5.8 |
Purified IgG from mice primed with 104 PFU of A/New Caledonia/20/99 virus (NC99) and then boosted 4 weeks later with 103 PFU of A/California/04/09 (Cal09) virus.
Purified IgG from mice primed with 104 PFU of A/New Caledonia/20/99 virus and then boosted 4 weeks later with 105 PFU of A/Solomon Islands/3/06 (SI06) virus.
Purified IgG from mice infected with 104 PFU of A/California/04/09 virus.
Stalk-specific monoclonal antibody 6F12 used as a positive control.
Purified IgG from naïve mice.