Table 3.
Demographic and clinical information for patients infected/colonized with KPC-2-KPa
| Patient (age [yr]/sex) | Hospital/isolate designation | Date (yr/mo/day) of: |
Underlying medical condition(s) | ICU related | Site of isolation/type of infection or colonization | Antibiotic regimen within 2 wk: |
Mortality |
|||
|---|---|---|---|---|---|---|---|---|---|---|
| Admission | KPC-KP isolation | Prior to KPC-KP isolation | After KPC-2-KP isolation | 14 days | In hospital | |||||
| 1 (22/M) | A/A1 | 2011/6/17 | 2011/6/20 | Becker muscular dystrophy, cardiac arrest after CPR, and ECMO | Yes | Wound/SSI (ECMO related) | Vancomycin, ceftazidime, piperacillin-tazobactam | Piperacillin-tazobactam, tigecycline, colistin | No | No |
| 2 (31/M) | A/A2 | 2011/6/18 | 2011/8/21 | DM, CKD, ARDS after ECMO | Yes | Sputum/colonization | Vancomycin, cefepime, colistin | Imipenem, colistin, moxifloxacin, vancomycin | No | Yes |
| 3 (81/F) | B/B1 | 2011/6/14 | 2011/7/2 | Colon cancer stage IV postoperation and chemotherapy, recurrence with bowel obstruction postoperation | Yes | Retroperitoneal abscess | Piperacillin-tazobactam | Doripenem, amikacin | No | Yes |
| 4 (83/F) | B/B2 | 2011/6/26 | 2011/7/25 | Colon cancer with liver and lung metastasis | Yes | Sputum/colonization | Piperacillin-tazobactam | Imipenem, gentamicin | No | Yes |
| 5 (67/M) | B/B3 | 2011/7/22 | 2011/8/9 | Subdural hemorrhage postoperation, dementia | Yes | Sputum/colonization | Piperacillin-tazobactam | Piperacillin-tazobactam | No | Np |
| 6 (45/M) | B/B4 | 2011/8/10 | 2011/9/5 | Cellulitis, acute myeloid leukemia postchemotherapy, neutropenic fever | No | Blood/bacteremia | Vancomycin, cefepime, metronidazole | Colistin, imipenem, amikacin | Yes | Yes |
| 7 (74/F) | B/B5 | 2011/7/9 | 2011/9/25 | COPD, stroke | Yes | Sputum/colonization | Piperacillin-tazobactam | Piperacillin-tazobactam | No | No |
| 8 (86/F) | B/B6 | 2011/9/23 | 2011/10/12 | DM, seizure, sick sinus syndrome post-pacemaker installation | Yes | Sputum/colonization | Piperacillin-tazobactam | Levofloxacin, trimethoprim- sulfamethoxazole | No | No |
| 9 (81/M) | C/C1 | 2011/5/17 | 2011/6/8 | DM, CAD, post-coronary artery bypass graft | Yes | Sputum | Piperacillin-tazobactam, amikacin | Amikacin | Yes | Yes |
| 10 (84/M) | C/C2 | 2011/6/17 | 2011/7/2 | DM, dissection of aorta | Yes | Sputum/colonization | Cefmetazole, cefepime, metronidazole | No | Yes | Yes |
| 11 (57/F) | C/C3 | 2011/5/1 | 2011/6/22 | DM, CAD, post-coronary artery bypass graft | Yes | Wound/SSI | Piperacillin-tazobactam, meropenem | Meropenem | No | Yes |
| 12 (84/F) | C/C4 | 2011/6/21 | 2011/6/24 | Pneumonia with respiratory failure | Yes | Urine/colonization | Ceftriaxone, sulbactam | Cefmetazole, amikacin | No | Yes |
| 13 (78/M) | C/C5 | 2011/6/28 | 2011/7/6 | Parkinson's disease, pneumonia with respiratory failure | Yes | Sputum/VAP | Piperacillin-tazobactam | Piperacillin-tazobactam, amikacin | No | No |
| 14 (89/M) | C/C6 | 2011/8/1 | 2011/8/1 | Pneumonia with septic shock | No | Sputum/VAP | Cefazolin | Imipenem | Yes | Yes |
| 15 (77/M) | C/C7 | 2011/7/28 | 2011/8/29 | Pressure sore, septic shock, UTI | Yes | Urine/UTI | Piperacillin-tazobactam, daptomycin | Doripenem | No | No |
| 16 (90/M) | D/D1 | 2011/8/2 | 2011/8/15 | CKD, urothelial carcinoma with lung and brain metastasis | Yes | Sputum/colonization | Cefazolin, cefoperazone-sulbactam | No | No | Yes |
a
ARDS, acute respiratory distress syndrome; CAD, coronary arterial disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CPR, cardiopulmonary resuscitation; DM, diabetes mellitus; ECMO, extracorporeal membrane oxygenation; F, female; ICU, intensive care unit; M, male; SSI, surgical site infection; UTI, urinary tract infection; VAP, ventilator-associated pneumonia.