Fig 1.

Activity of SMX and TMP against M. tuberculosis H37Rv. (A) M. tuberculosis H37Rv cultures were treated with SMX or TMP and incubated at 37°C for 3 weeks. CFU were determined by plating 10-fold serial dilutions of each culture onto Middlebrook 7H10 agar plates. Each growth curve was done at least in triplicate, and the average with standard deviation was plotted. (B) M. tuberculosis H37Rv was treated with a combination of SMX and TMP. Conditions for the experiment were the same as those for panel A. Concentrations are given in μg/ml.