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Population parameter valuesa
| Parameter (unit) | Mean | Median | Standard deviation |
|---|---|---|---|
| Volume (liter) | 20.61 | 16.82 | 15.27 |
| K12 (h−1) | 1.94 | 1.12 | 3.00 |
| K21 (h−1) | 15.34 | 15.31 | 12.71 |
| Clearance (liter/h) | 1.60 | 1.36 | 0.85 |
| K23 (h−1) | 11.35 | 3.59 | 10.31 |
| K32 (h−1) | 5.69 | 0.24 | 9.90 |
These estimates are from the overall model fitted to patients receiving an intermittent and conventional regimen.
