Table 1.
MICs of β-lactam and non-β-lactam antibiotics for the mecALGA251 MRSA isolates, determined by broth microdilution
| Antimicrobial class and agent | MIC range (μg/ml) |
|---|---|
| β-lactams | |
| Penicillins | |
| Penicillin | 0.4–8 |
| Oxacillin | 0.35–32 |
| Cephalosporins | |
| Cefoxitin | >8–64 |
| Non-β-lactams | |
| Glycopeptides | |
| Vancomycin | 0.5–1 |
| Teicoplanin | 0.5–1 |
| Lincosamides | |
| Clindamycin | 0.125–0.25 |
| Oxazolidinones | |
| Linezolid | 0.125–0.5 |
| Rifamycins | |
| Rifampin | 0.004–0.008 |
| Fosfomycins | |
| Fosfomycin | 1.2–9.6 |
| Folate pathway inhibitors | |
| Trimethoprim-sulfamethoxazole | 0.024–0.48 |
| Aminoglycosides | |
| Gentamicin | 0.2–0.4 |
| Tobramycin | 0.256–0.512 |
| Fluoroquinolones | |
| Ciprofloxacin | 0.08–0.16 |
| Levofloxacin | 0.2–0.4 |
| Moxifloxacin | 0.04–0.08 |
| Macrolides | |
| Erythromycin | 0.025–0.4 |
| Monoxycarbolic acids | |
| Mupirocin | 0.128–0.256 |
| Tetracyclines | |
| Tetracycline | 0.125–1 |
| Nitrofurans | |
| Nitrofurantoin | >2–8 |
| Others | |
| Fusidic acid | 0.064–0.128 |