Table 3.
Possible bacterial species associated with initiating and driving Crohn's disease in the CD patients in this studya
| Patient | Possible agents associated with disease |
|---|---|
| CD1 | Campylobacter concisus; Pseudomonas balearica; Cupriavidus gilardii |
| CD2 | Fusobacterium equinum (27.4%); Klebsiella spp. |
| CD3 | Cupriavidus gilardii; Pseudomonas balearica; Massilia timonae; Fusobacterium equinum |
| CD4 | Ruminococcus torques (21.1%) |
| CD5 | Klebsiella variicola; Escherichia fergusonii; Bacteroides spp. (73.7%); Fusobacterium canifelinum |
| CD6 | Massilia timonae; Escherichia fergusonii; Bilophila wadsworthia; Collinsella aerofaciens (8.2%); Fusobacterium canifelinum |
| CD7 | Cupriavidus gilardii; Pseudomonas balearica; Massilia timonae; Escherichia fergusonii; Clostridium difficile (6.5%) |
| CD8 | Campylobacter concisus; Clostridium difficile (24.7%); Cupriavidus gilardii; Pseudomonas balearica; Massilia timonae; Klebsiella spp.; Escherichia fergusonii |
| CD9 | Streptococcus spp. (74.0%) |
| CD10 | Klebsiella spp.; Escherichia fergusonii; Bacteroides spp. (50.2%); Fusobacterium canifelinum |
| CD11 | Citrobacter unclassified (46.2%); Escherichia fergusonii; Klebsiella spp.; Pseudomonas balearica; Massilia timonae |
| CD12 | Bilophila wadsworthia; Fusobacterium canifelinum |
| CD13 | Clostridium difficile (2.2%) |
| CD14 | Escherichia coli; Shigella sonnei; Fusobacterium nucleatum; Fusobacterium periodonticum; Peptostreptococcus anaerobius (13.9%) |
| CD15 | Unusual Alphaproteobacteria detected |
| CD16 | Escherichia coli; Shigella sonnei; Bacteroides spp. (56.3%) |
| CD17 | Escherichia coli; Shigella sonnei |
| CD18 | Bacteroides spp. (30.0%) |
| CD19 | Clostridium rectum (Fusobacteria); Bacteroides spp. (57.1%); Parabacteroides spp. (19.1%) |
a
These bacteria were chosen based on their previous association with CD in other studies, their pathogenic potential in humans, or their relative abundance in CD patients versus controls in this study.