Table 5.
Calculated positive and negative predictive values for FilmArray RP and DFCI/BWH clinically indicated testing
| Sample typea | Test | Calculated positive predictive value (CI)b | Calculated negative predictive value (CI)b |
|---|---|---|---|
| Allc | DFCI/BWH | 1.00 (0.79, 1.00) | 0.84 (0.74, 0.91) |
| FilmArray RP | 0.86 (0.68, 0.96) | 1.00 (0.95, 1.00) | |
| BALc | DFCI/BWH | 1.00 (0.37, 1.00) | 0.90 (0.78, 0.97) |
| FilmArray RP | 0.89 (0.52, 1.00) | 1.00 (0.93, 1.00) | |
| NPA | DFCI/BWH | 1.00 (0.74, 1.00) | 0.71 (0.49, 0.87) |
| FilmArray RP | 0.85 (0.62, 0.97) | 1.00 (0.81, 1.00) |
a
BAL, bronchoalveolar lavage; NPA, nasopharyngeal aspirate.
b
The estimated positive and negative predictive values did not change much when the second sample obtained from the three patients who underwent testing twice was excluded. CI, confidence interval.
c
These estimates excluded the three samples in which parainfluenza virus 2 and parainfluenza virus 3 were detected by clinical testing but not by FilmArray RP assay, since verification testing did not test for either of these pathogens.