Table 2.
Pathways represented by genes that are altered during proliferation arrest in 3D cultures
| Pathway | No. of proteins |
P value | FDR | Gene IDs | |
|---|---|---|---|---|---|
| In pathway | From study | ||||
| Ceramide signaling | 47 | 7 | 1.338e−04 | 3.600e−02 | AIFM1, BID, BIRC3, MYC, NFKBIA, PDGFA, PRKRA |
| Pathogenic E. coli infection | 26 | 5 | 3.989e−04 | 4.850e−02 | ACTB, TUBA1B, TUBB, TUBB2C, TUBB3 |
| Tumor necrosis factor receptor signaling | 272 | 16 | 6.667e−04 | 5.567e−02 | AIFM1, BCL3, BID, BIRC3, CYLD, FOS, LYN, MYC, NFKBIA, PDGFA, PPARG, PRKCH, PRKRA, PTPRK, SLC3A2, SQSTM1 |
| Sphingosine 1-phosphate | 130 | 10 | 1.041e−03 | 7.250e−02 | AIFM1, BID, BIRC3, FOS, GRB10, LYN, MYC, NFKBIA, PDGFA, PRKRA |