Fig 4.

The antrum harbors lower H. pylori colonization than other regions and more severe inflammation. (A) H. pylori colonization levels as CFU/gram of stomach from female C57BL/6N mice infected for 3 months (symbols surrounded by boxes) or 6 months (symbols without boxes) with H. pylori strain SS1 or its isogenic Che⁻ mutant. n = 7 for the wild type, n = 8 for the Che⁻ mutant. (B) Gastric inflammation tissue from mice infected for 6 months was analyzed by a pathologist and graded for inflammation. Error bars indicate standard error of the mean. Data derived from the same 6-month-infected mice as presented in panel A. L.D. = limit of detection. n = 5 for the wild type and the Che⁻ mutant. *, P < 0.05 (Student's t test).