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Production of cytokines at different time points by bone marrow-derived macrophages in response to wild-type and Tx5 N. brasiliensis (A through D) or to increasing concentrations of isolated wall-associated lipids from N. brasiliensis (E through H). Control BMDM were uninfected or unstimulated with lipids (0 μg in panels E through H). Data expressed as means ± standard deviations. *, P < 0.05; **, P < 0.001; ***, P < 0.0001 as assessed using a Bonferroni posttest.
