Table 2.
Characterization of 3-Chloro-4-[(4-methoxyphenyl)amino]furo[2,3-b]quinoline-loaded solid lipid nanoparticles (SLNs) with or without polyethylene glycol (PEG) in terms of the diameter of particle size (d), polydispersity index (PDI), zeta potential, and entrapment efficiency (EE%), and stability changes following storage at room temperature (25°C) for 1 month
| Formulation | d (nm) | PDI | Zeta potential (mV) | EE% | ||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||
| 0 day | 1 month | 0 day | 1 month | 0 day | 1 month | 0 day | 1 month | |
| SLNs without PEG | 47.3 ± 0.5 | 42.4 ± 0.4 | 0.18 ± 0.01 | 0.18 ± 0.01 | 22.5 ± 1.5 | 20.9 ± 1.8 | 99.69 ± 0.12 | 80.59 ± 1.20 |
| SLNs with PEG | 28.0 ± 0.6 | 28.7 ± 0.3 | 0.13 ± 0.02 | 0.20 ± 0.01 | 27.8 ± 6.4 | 25.4 ± 3.3 | 99.98 ± 0.00 | 91.63 ± 2.36 |
Note: Each value represents the mean ± standard deviation (n = 3).