Table 3.
Postoperative complications and tolerance to systemic treatment
| RFA plus systemic treatment (N = 57) |
Systemic treatment (N = 59) | |||
|---|---|---|---|---|
| RFA (N = 30), N (%) | RFA plus resection (N = 27)a, N (%) | Total (N = 57), N (%) | ||
| Postoperative complications | ||||
| Respiratory failure | 0 (0.0) | 1 (3.7) | 1 (1.8) | |
| Cardiac failure or infarction | 1 (3.3) | 2 (7.4) | 3 (5.3) | |
| Hepatic dysfunction bilirubin >10 mg/dl for 3 days | 1 (3.3) | 2 (7.4) | 3 (5.3) | |
| Wound infection | 2 (6.7) | 1 (3.7) | 3 (5.3) | |
| Intra-abdominal infection (abscess) | 1 (3.3) | 1 (3.7) | 2 (3.5) | |
| Other infection | 1 (3.3) | 0 (0.0) | 1 (1.8) | |
| Fever | 5 (16.7) | 7 (25.9) | 12 (21.1) | |
| Malaise | 1 (3.3) | 1 (3.7) | 2 (3.5) | |
| Fatigue | 4 (13.3) | 2 (7.4) | 6 (10.5) | |
| Hemorrhage | 0 (0.0) | 2 (7.4) | 2 (3.5) | |
| Need for reoperation | 0 (0.0) | 3 (11.1) | 3 (5.3) | |
| Renal failure | 0 (0.0) | 1 (3.7) | 1 (1.8) | |
| Other | 2 (6.7) | 3 (11.1) | 5 (8.8) | |
| Hospitalization >24 h: due to complication | 4 (13.3) | 6 (22.2) | 10 (17.5) | |
| Postoperative death | 0 (0.0) | 1 (3.7) | 1 (1.8) | |
| Tolerance to systemic treatment | (N = 51) N (%) | (N = 59) N (%) | ||
| Grade 3–4 neutropenia | 14 (27.5) | 12 (20.3) | ||
| Grade 3–4 cardiotoxicity | 5 (9.8) | 1 (1.7) | ||
| Grade 3–4 diarrhea | 10 (19.6) | 10 (16.9) | ||
| Grade 3–4 vomiting | 5 (9.8) | 4 (6.8) | ||
| Grade 3 nausea (no grade 4) | 7 (13.7) | 6 (10.2) | ||
| Grade 3–4 gastrointestinal others | 4 (7.8) | 4 (6.8) | ||
| Grade 3–4 pulmonary | 3 (5.9) | 1 (1.7) | ||
| Grade 3–4 renal | 1 (2.0) | 1 (1.7) | ||
| Grade 3 neuropathy (no grade 4) | 9 (17.6) | 8 (13.6) | ||
| Grade 3 fatigue (no grade 4) | 7 (13.7) | 4 (6.8) | ||
| Grade 3 hypertension (no grade 4) | 2 (3.9) | 2 (3.4) | ||
Patients may have several complications; therefore, number of complications does not add up to the total number of patients.
aOne patient treated by resection only.
RFA, radiofrequency ablation.