Table A1.
Variable | AIs First v Tamoxifen First |
|
---|---|---|
RR | 95% CI | |
Age at diagnosis, years | ||
55-64 | 1 | Reference |
65-74 | 0.78 | 0.60 to 1.00 |
≥ 75 | 0.67 | 0.46 to 0.97 |
BMI, kg/m2 | ||
< 25.0 | 1 | Reference |
25.0-29.9 | 1.11 | 0.80 to 1.54 |
≥ 30.0 | 1.40 | 1.06 to 1.87 |
Stage at diagnosis | ||
I | 1 | Reference |
IIA | 1.21 | 0.66 to 2.23 |
IIB | 2.02 | 0.74 to 5.46 |
Tumor size, cm | ||
< 1.0 | 1 | Reference |
1.0-1.9 | 1.06 | 0.77 to 1.45 |
≥ 2.0 | 0.84 | 0.48 to 1.48 |
Lymph node status | ||
Negative | 1 | Reference |
Positive | 0.89 | 0.50 to 1.59 |
Definitive surgical procedure | ||
Breast conservation | 1 | Reference |
Mastectomy | 1.08 | 0.76 to 1.53 |
Chemotherapy | ||
No | 1 | Reference |
Yes | 0.99 | 0.76 to 1.28 |
Radiation therapy | ||
No | 1 | Reference |
Yes | 0.94 | 0.76 to 1.28 |
Charlson score | ||
0 | 1 | Reference |
1 | 1.20 | 0.91 to 1.58 |
≥ 2 | 0.87 | 0.58 to 1.28 |
Year of diagnosis | ||
2001 | 1 | Reference |
2002 | 1.80 | 0.92 to 3.52 |
2003 | 1.32 | 0.65 to 2.39 |
2004 | 2.84 | 1.50 to 5.38 |
2005 | 4.04 | 2.21 to 7.38 |
2006 | 3.77 | 2.06 to 6.88 |
2007 | 4.15 | 2.26 to 7.60 |
2008 | 4.24 | 2.26 to 7.95 |
Abbreviations: AI, aromatase inhibitor; BMI, body mass index; RR, relative risk.
* All variables in the table are adjusted for each other.