Table 2.
Comparison of groups categorized based on the presence of elevated LDL-C levels and hypertriglyceridemia
| Elevated LDL-C levels/hypertriglyceridemia |
Group A |
Group B |
Group C |
Group D |
Pvalue |
|---|---|---|---|---|---|
| (−)/(−) (n = 216) | (+)/(−) (n = 120) | (−)/(+) (n = 95) | (+)/(+) (n = 45) | ||
| Lipid profiles |
|
|
|
|
|
| TG (mg/dl) |
91.1 [85.1−96.7] |
98.1 [90.5−105.6] |
229.3 [220.8−237.8] |
219.0 [206.7−231.4] |
< 0.001 |
| HDL-C (mg/dl) |
59.3 [57.6−61.1] |
56.8 [54.4−59.1] |
49.3 [46.7−52.0] |
48.9 [45.1−52.7] |
< 0.001 |
| LDL-C (mg/dl) |
114.2 [111.8−116.7] |
162.5 [159.2−165.8] |
112.1 [108.4−115.8] |
159.1 [153.8−164.5] |
< 0.001 |
| Sd-LDL-C (mg/dl) |
33.8 [31.9−35.6] |
49.6 [47.2−52.1] |
51.9 [49.2−54.7] |
68.5 [64.5−72.5] |
< 0.001 |
| Sd-LDL-C/LDL-C |
0.30 [0.28−0.31] |
0.30 [0.29−0.32] |
0.47 [0.45−0.48] |
0.43 [0.40−0.46] |
< 0.001 |
| TC (mg/dl) |
191.8 [188.7−194.8] |
238.9 [234.8−243.1] |
207.3 [202.7−212.0] |
251.8 [245.1−258.6] |
< 0.001 |
| Apolipoprotein B (mg/dl) |
82.8 [75.5−80.4] |
112.6 [110.3−114.9] |
99.4 [96.8−102.0] |
126.3 [122.5−130.1] |
< 0.001 |
| Demographics, clinical characteristics, and laboratory data | |||||
| Age (years) |
57.4 [56.2−58.7] |
56.1 [54.4−57.8] |
54.3 [52.4−56.3] |
51.5 [48.7−54.3] |
< 0.001 |
| BMI (kg/m2) |
23.6 [23.2−24.0] |
24.0 [23.4−24.5] |
25.1 [24.5−25.7] |
25.7 [24.8−26.6] |
< 0.001 |
| Obesity (% of subjects) |
31.0 |
30.8 |
46.3 |
62.2 |
< 0.001 |
| Glucose (mg/dl) |
103.8 [101.4−106.1] |
105.2 [102.1−108.4] |
113.5 [110.0−117.1] |
111.5 [106.4−116.7] |
< 0.001 |
| Hyperglycemia |
|
|
|
|
|
| (% of subjects) |
22.7 |
27.5 |
37.9 |
44.4 |
0.004 |
| ALT (IU/L) |
24.3 [22.0−26.6] |
27.4 [24.3−30.5] |
34.4 [30.9−37.9] |
34.6 [29.5−39.6] |
< 0.001 |
| γ-GTP (IU/L) |
35.3 [29.4−41.2] |
38.6 [30.7−46.5] |
70.0 [61.2−78.9] |
59.6 [46.8−72.5] |
< 0.001 |
| Fatty liver (% of subjects) |
25.9 |
43.3 |
61.1 |
53.3 |
< 0.001 |
| Hypertension |
|
|
|
|
|
| (% of subjects) |
53.7 |
54.2 |
57.9 |
55.6 |
0.919 |
| Current alcohol consumption |
|
|
|
|
|
| (% of subjects) |
38.4 |
54.2 |
46.3 |
33.3 |
0.153 |
| Current smokers |
|
|
|
|
|
| (% of subjects) | 28.7 | 30.0 | 28.4 | 24.4 | 0.919 |
Data are expressed as means [95% CIs] or percentages. $, LDL-C levels were calculated using the Friedwald formula.
Continuous variables were compared by ANOVA and categorical variables were compared by Chi-square tests.