Table 3.
Comparison of the remodeling and hypertrophic response in aortic stenosis patients with and without concomitant hypertension
| Hypertension | No Hypertension | P value | |
|---|---|---|---|
| Number |
37 |
54 |
- |
| Male Sex % |
23 (62%) |
34 (62%) |
1.00 |
| Age (years) |
70 ± 13 |
55 ± 21 |
<0.01* |
| Aortic Valve Area (cm2) |
1.00 ± 0.33 |
0.88 ± 0.31 |
0.09 |
| Indexed LVEDV (ml/m2) |
76 ± 24 |
78 ± 29 |
0.74 |
| LV mass index (g/m2) |
102 ± 28 |
93 ± 25 |
0.08 |
| M/V (g/ml) |
1.41 ± 0.37 |
1.27 ± 0.38 |
0.10 |
| Maximal wall thickness (mm) |
16 ± 3 |
14 ± 3 |
<0.01* |
| Asymmetric Wall Thickening n (%) |
16 (43%) |
9 (17%) |
0.01* |
| Pattern of Remodeling/Hypertrophy | |||
| Normal n (%) |
1 (3%) |
10 (19%) |
0.02* |
| Remodeling n (%) |
9 (24%) |
13 (24%) |
1.00 |
| Concentric n (%) |
2 (5%) |
9 (17%) |
0.19 |
| Asymmetric n (%) |
7 (19%) |
4 (7%) |
0.11 |
| Hypertrophy n (%) |
22 (59%) |
26 (48%) |
0.39 |
| Concentric Hypertrophy n (%) |
13 (35%) |
21 (39%) |
0.83 |
| Asymmetric Hypertrophy n (%) |
9 (24%) |
5 (9%) |
0.07 |
| LV Decompensation n (%) | 5 (14) | 5 (9%) | 0.73 |
Categorical variables expressed as n (%) and compared using Fisher’s exact test. Continuous variables expressed as the mean ± SD and compared using the Student’s unpaired t-test. *P < 0.05.