Table 4.
Comparison of patient characteristics between those with asymmetric and concentric forms of hypertrophy and remodeling in aortic stenosis
| Concentric | Asymmetric | p-value | |
|---|---|---|---|
| Number |
45 |
25 |
- |
| Age (years) |
56 ± 19 |
72 ± 11 |
<0.01* |
| Male sex (%) |
62 |
68 |
0.41 |
| LV mass index (g/m2) |
103 ± 25 |
96 ± 25 |
0.23 |
| Max wall thickness (mm) |
15 ± 3 |
17 ± 2 |
<0.01* |
| Hypertrophy (%) |
76 |
56 |
0.09 |
| Aortic valve area (cm2) |
0.96 ± 0.36 |
0.96 ± 0.30 |
0.83 |
| Ejection Fraction |
72 ± 12 |
71 ± 15 |
0.79 |
| Indexed LVEDV (mL/m2) |
72 ± 20 |
69 ± 22 |
0.57 |
| Hypertension (%) |
33 |
64 |
0.01* |
| Diabetes Mellitus (%) |
11 |
12 |
0.91 |
| ACE inhibitor/ARB use (%) |
33 |
45 |
0.45 |
| Beta-blocker (%) | 16 | 27 | 0.32 |
Asymmetric left ventricular wall thickening was defined as a regional wall thickening ≥13 mm that was >1.5-fold the thickness of the opposing myocardial segment. Criteria had to be fulfilled on two adjacent short-axis slices.