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. 2012 Sep 25;7(9):e46076. doi: 10.1371/journal.pone.0046076

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© 2012 Gui et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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DNAs from the lung tissues of SPC-Cre-ER^T2/TSC1^fx/fx transgenic mice treated with vehicle or tamoxifen were examined by PCR to detect TSC1 deletion as an indication of Cre-ER^T2 recombinase activity. M, DNA marker; +, a transgenic mouse with TSC1 deletion; -, C57BL/6J mouse. Other lanes, offspring from F42 and F67 founders treated with vehicle (vehi) or tamoxifen (tam).