Figure 7. La³⁺ and Gd³⁺ suppress store-operated Ca²⁺ entry stimulated by ATP in endothelial progenitor cells.

La³⁺ (10 µM) and Gd³⁺ dampen SOCE triggered by ATP (100 µM) in both N-EPCs (A) and RCC-EPCs (B). The traces are representative of the experiments conducted on EPCs from at least three different donors for each condition. Mean±SE of the amplitude of ATP-induced Ca²⁺ release and ATP-induced SOCE in the absence and presence of each trivalent cation in both N-EPCs (C) and RCC-EPCs (D). The asterisk indicates p<0.05.