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. 2012 Sep 25;7(9):e45591. doi: 10.1371/journal.pone.0045591

Figure 2. MicroRNA modulation in premalignant 16 wk miRNA predicts future neoplasia development.

Figure 2

MicroRNA analysis was done on colonic biopsies from AOM rats at a preneoplastic (16 wk) time point. The rats were followed for 40 weeks and separated as tumor bearing and non-bearing AOM rats. The miRNA expression at the premalignant stage (16 wk) was then compared between the control rats and the AOM rats which eventually developed tumors or remained non-tumor bearing. *: p<0.05 when compared to normal saline controls. Specific p values are given in which AOM rats without tumors are compared to AOM rats with tumors.