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. 2012 Sep 25;7(9):e45788. doi: 10.1371/journal.pone.0045788

Table 4. Crude and adjusted Hazard Ratios (HR) with 95% confidence intervals (CI) for cancer mortality, smoking and non-smoking related, in relation to mental and non-mental sick-leave diagnoses.

Sickness absence in 2005 Death Model 0 Model 1 Model 2 Model 3
N, % HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI)
All cancer deaths
No sickness absence 7070 (0.16) 1 1 1 1
Non-mental diagnoses1 3475 (1.02) 7.83 (7.52–8.16) 6.05 (5.8–6.3) 3.16 (3.03–3.31) 1.86 (1.75–1.98)
Mental diagnoses 173 (0.22) 1.74 (1.5–2.02) 1.72 (1.48–2.00) 1.48 (1.27–1.72) 1.21 (1.01–1.45)
Substance - rel. disorders2 10 (0.5) 3.90 (2.1–7.25) 2.76 (1.48–5.13) 1.98 (1.06–3.71) 1.58 (0.75–3.36)
Affective disorders (F30–F39) 51 (0.19) 1.48 (1.12–1.95) 1.47 (1.11–1.93) 1.17 (0.89–1.55) 0.94 (0.68–1.31)
Neurotic/somatoform disorders* 12 (0.14) 1.12 (0.64–1.97) 1.48 (0.84–2.61) 1.25 (0.71–2.21) 1.05 (0.55–2.03)
Stress - related disorders (F43) 90 (0.25) 1.91 (1.55–2.36) 1.81 (1.47–2.23) 1.67 (1.35–2.05) 1.34 (1.05–1.71)
Other psychiatric disorders 10 (0.28) 2.19 (1.18–4.07) 2.26 (1.22–4.20) 2.00 (1.07–3.72) 1.97 (1.02–3.79)
Smoking - rel. cancer
No sickness absence 2872 (0.06) 1 1 1 1
Non - mental diagnoses1 1227 (0.36) 6.79 (6.34–7.27) 5.10 (4.76–5.46) 3.05 (2.83–3.28) 1.59 (1.43–1.77)
Mental diagnoses 63 (0.08) 1.56 (1.21–2.00) 1.63 (1.27–2.09) 1.37 (1.06–1.76) 1.17 (0.87–1.56)
Substance - rel. disorders2 7 (0.35) 6.7 (3.19–14.07) 4.2 (2.00–8.82) 2.58 (1.21–5.5) 2.15 (0.87–5.3)
Affective disord. (F30–F39) 15 (0.06) 1.07 (0.64–1.77) 1.11 (0.67–1.84) 0.87 (0.52–1.44) 0.67 (0.36–1.25)
Neurotic/somatoform disorders* 7 (0.08) 1.60 (0.76–3.37) 2.26 (1.08–4.76) 1.83 (0.87–3.84) 1.79 (0.8–4.00)
Stress - rel. disorders (F43) 33 (0.09) 1.72 (1.22–2.43) 1.77 (1.25–2.49) 1.63 (1.16–2.30) 1.45 (0.99–2.12)
Other psychiatric disorders 1 (0.03) 0.54 (0.08–3.81) 0.58 (0.08–4.12) 0.5 (0.07–3.56)
Not Smoking-rel. cancer
No sickness absence 4198 (0.09) 1 1 1 1
Non - mental diagnoses1 2248 (0.66) 8.55 (8.11–9.01) 6.71 (6.37–7.08) 3.23 (3.06–3.42) 2.01 (1.86–2.17)
Mental diagnoses 110 (0.14) 1.87 (1.54–2.26) 1.79 (1.48–2.16) 1.55 (1.28–1.88) 1.24 (0.99–1.56)
Substance - rel. disorders2 3 (0.15) 1.97 (0.64–6.12) 1.51 (0.49–4.68) 1.22 (0.39–3.81) 0.91 (0.22–3.68)
Affective disorders (F30–F39) 36 (0.13) 1.76 (1.27–2.44) 1.71 (1.23–2.37) 1.38 (0.99–1.92) 1.13 (0.76–1.66)
Neurotic/somatoform disorders* 5 (0.06) 0.79 (0.33–1.89) 1.00 (0.42–2.41) 0.87 (0.36–2.11) 0.58 (0.19–1.80)
Stress - related disorders (F43) 57 (0.16) 2.04 (1.57–2.66) 1.85 (1.42–2.41) 1.69 (1.30–2.20) 1.28 (0.94–1.75)
Other psychiatric disorders 9 (0.25) 3.32 (1.73–6.39) 3.34 (1.74–6.43) 3.00 (1.56–5.79) 3.26 (1.69–6.29)

Model 0: Crude; Model 1: Adjusted for age, sex, educational level, family situation, region, country of birth; Model 2: As model 1 and adjusted for inpatient and outpatient care due to mental and cancer diagnoses as well as non-mental/non - cancer diagnoses. Model 3: like model 2 but with a 2 years -wash-out period;

*

F40–F42, F44–F49,

1

Including sick-leave spells for which diagnoses are missing;

2

including F10–F19.