Table 3. Comparison of IHC scores for Ep-ICD, EpEx and ESLI in thyroid tissues.

Group	Membranous EpEx(Mean ± SEM)	Cytoplasmic Ep-ICD(Mean ± SEM)	Nuclear Ep-ICD(Mean ± SEM)	ESLI(Mean ± SEM)
Benign	6.8±0.1	3.3±0.4	0.9±0.2	4.5±0.6
Malignant	4.6±0.1	5.1±0.1	2.0±0.1	9.6±0.2
Non-aggressive PTC	6.1±0.1	4.8±0.1	1.0±0.1	6.7±0.3
Aggressive PTC	3.7±0.1	5.3±0.1	2.5±0.1	11.0±0.2

Mann-Whitney test p value for benign vs. PTC: cytoplasmic Ep-ICD p = 0.000; nuclear Ep-ICD p = 0.002 and ESLI p = 0.000. p value for Aggressive vs. Non-aggressive PTC: cytoplasmic Ep-ICD p = 0.000; nuclear Ep-ICD p = 0.000 and ESLI p = 0.000.