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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Stroke. 2012 Jul 24;43(10):2757–2763. doi: 10.1161/STROKEAHA.112.653857

Figure 2.

Figure 2

A. Dynamic ADC changes during H-I and reperfusion-reoxygenation in E22, E25, E29 fetuses that were born alive with motor deficits. Duration of H-I was 40 min for E22 and E25 fetuses (gray bar) and 32 min for E29 fetuses (black bar). With increasing age there is an earlier and deeper fall in ADC during H-I.

B. Fetuses that developed motor deficits later showed a pattern of ADC different from sham controls (not shown), non-hypertonic and stillbirths with 32 min H-I at E29.

C. The onset of rapid phase of ADC decline during H-I occurred significantly earlier at E29 than at E22. * - p<0.05 in E29 group compared with E22

D. The lowest value of ADC during time course (nadir) was lower in E29 compared to E22 (* p<0.05). The ADC value at 20 min reperfusion progressively decreased with increasing gestational age. ** - p <0.05 in E25 group compared with E22 and E29 groups. ANOVA with Tukey post-hoc group comparisons.