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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Gastroenterology. 2012 Jun 23;143(4):1006–1016.e4. doi: 10.1053/j.gastro.2012.06.034

Figure 5. Alteration of intestinal microbiota results in delayed colonic motility.

Figure 5

WT and Tlr4Lps-d mice treated with water or antibiotics (ampicillin and neomycin) for twelve weeks were studied to assess rate of gastrointestinal motility. Parameters measured include (A) Stool retention, (B) Pellet number, and (C) Nitrergic relaxation in response to EFS. (D) Whole mount staining data for nNOS and TUJ1 positive neurons. (E) Endotoxin measurement in WT mice in the presence or absence of antibiotic treatment. (F) Total bacterial content in the stool of mice treated with or without antibiotics. Values are mean ± SE. n = 5 or 6. *P < 0.05; **P < 0.01; ***P < 0.001.