Table 22.
Enhancement of antibiotic activity by glycyrrhizin (1 μg/mL) in combination with antibiotics against different organisms [154, 155].
| Organisms | Antibiotics | Concentration (μg/mL) | Fold enhancement of activity |
|---|---|---|---|
| E. coli (ATCC 10536) | Rifampicin | 10.0 | 3.8 |
| Rifampicin | 20.0 | 14.0 | |
| Nalidixic acid | 8.0 | 9.5 | |
| Ampicillin | 6.0 | 12.6 | |
| Ampicillin | 8.0 | 2.1 | |
| Tetracycline | 2.0 | 1.9 | |
| Tetracycline | 4.0 | 9.0 | |
| B. subtilis (ATCC 6015) | Nalidixic acid | 6.0 | 4.5 |
| Nalidixic acid | 8.0 | 6.75 | |
| Tetracycline | 1.0 | 5.0 | |
| M. smegmatis (ATCC 14468) | Rifampicin | 0.5 | 6.5 |
| Nalidixic acid | 4.0 | 7.7 | |
| Tetracycline | 0.5 | 1.5 |